[robertprice]

Pop-Eye is a symptom not a disease, and it can be very frustrating to determine what causes it. The culprit can be anything from bad water chemistry, dirty water, bacterial septicemia, vibrio, Hemamita or hole-in-the-head, eye flukes and fish TB. I recently lost lost a Flowerhorn from unilateral pop-peye in 9 days. I used tetracycline, prazi-pro, flagyl and clout and it died anyhow. It's mate is fine. I'm suspicious it had advanced Hexamita or TB. Kanamycin is about the only thing that knocks out fish TB.